2022 Indianapolis 500 Odds, Picks & Indy 500 Betting Predictions

It’s the biggest auto race in America, full of the requisite pageantry and prestige.

The "Greatest Spectacle in Racing" is mere hours away as Indianapolis Motor Speedway will bring back a full house for the 106th running of the Indianapolis 500.

Driver Win Top 3 Top 5 Scott Dixon +400 +135 -140,  Alex Palou +450 +145 -125, Patricio O’Ward +850 +260 +145,  Josef Newgarden +1000 +260 +145,  Rinus VeeKay +1200 +260 +145,  Marcus Ericsson +1400 +400 +230,  Will Power +1400 +350 +200,  Colton Herta +1600 +400 +230

While Dixon is considered one of the foremost IndyCar racers of his era.

New Zealander has claimed the Borg-Warner just once (2008) in 19 career starts despite being consistently one of the fastest drivers at Indianapolis

The seven-time NASCAR champ Johnson is a 500 rookie and has struggled for most of his two-season dalliance in IndyCars.

Palou qualified on the front row, has been consistently fast in practice, and has none of the baggage of his teammate, swinging our winner’s pick to the Spaniard—who also carries a bit better value on betting sites.

The 106th Indy 500 begins at 12:30 p.m. ET. The green flag is scheduled to wave at 12:45 p.m. ET.

NBC is broadcasting the event and will have a pre-race show beginning at 11 a.m. ET.